지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Preventive Nutrition and Food Science Preventive Nutrition and Food Science Vol.20 No.3
- 발행연도
- 2015.9
- 수록면
- 190 - 197 (8page)
이용수
초록· 키워드
오류제보하기
The aim of this study was to investigate the acute and subacute oral toxicity of crude antifungal compounds produced by Lactobacillus plantarum HD1 in Sprague-Dawley rats. In the acute toxicity study, the crude antifungal compounds (0.625, 1.25, 2.5, and 5.0 g/kg) did not produce mortality, significant changes in general behavior, or changes in the gross appearance of the organs. In the subacute toxicity study, the crude antifungal compounds were administered orally to rats at doses of 0, 0.5, 1.0, and 2.0 g/kg daily for 28 days. There were no test article-related deaths, abnormal clinical signs, or body weight changes. The study also showed no significant differences between the control and treated groups in hematological and serum biochemical parameters, histopathological examination, or any other findings. These results suggest that acute or subacute oral administration of crude antifungal compounds from L. plantarum HD1 is not toxic in rats.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS AND DISCUSSION
REFERENCES
참고문헌 (31)
참고문헌 신청
[학술지(정기간행물)] - Schilter B / 2003 / Guidance on Safety assessment of botanicals and botanical preparations intended for use as ingredients in food supplements / Food Chem Toxicol 41 : 1625 ~ 1649
[학술지(정기간행물)] - Dalié DKD / 2010 / Lactic acid bacteria-potential for control of mould growth and mycotoxins : a review / Food Control 21 : 370 ~ 380
[학술지(정기간행물)] - Voulgari K / 2010 / Antifungal activity of non-starter lactic acid bacteria isolates from dairy products / Food Control 21 : 136 ~ 142
[학술지(정기간행물)] - Yang EJ / 2010 / Purification of a new antifungal compound produced by Lactobacillus plantarum AF1 isolated from kimchi / Int J Food Microbiol 139 : 56 ~ 63
[학술지(정기간행물)] - Brul S / 1999 / Preservative agents in foods : mode of action and microbial resistance mechanisms / Int J Food Microbiol 50 : 1 ~ 17
[학술지(정기간행물)] - Dalié DKD / 2010 / Lactic acid bacteria-potential for control of mould growth and mycotoxins : a review / Food Control 21 : 370 ~ 380
[학술지(정기간행물)] - Voulgari K / 2010 / Antifungal activity of non-starter lactic acid bacteria isolates from dairy products / Food Control 21 : 136 ~ 142
[학술지(정기간행물)] - Yang EJ / 2010 / Purification of a new antifungal compound produced by Lactobacillus plantarum AF1 isolated from kimchi / Int J Food Microbiol 139 : 56 ~ 63
[학술지(정기간행물)] - Brul S / 1999 / Preservative agents in foods : mode of action and microbial resistance mechanisms / Int J Food Microbiol 50 : 1 ~ 17
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UCI(KEPA) : I410-ECN-0101-2016-594-001972832