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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Preventive Nutrition and Food Science Preventive Nutrition and Food Science Vol.20 No.3
- 발행연도
- 2015.9
- 수록면
- 198 - 203 (6page)
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초록· 키워드
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The present study was conducted to assess the status of vitamin C among healthy young adults in relation to serum antioxidant parameters [glutathione (GSH), thiols, and total antioxidant capacity, (TAC)], and oxidative stress markers [malondialdehyde (MDA), and nitrites plus nitrates (NN)]. A prospective study included 200 young adults, and their dietary intake was assessed by using food diaries. Fasting plasma vitamin C, serum levels of GSH, thiols, TAC, MDA, and NN were measured using biochemical assays. It was observed that 38% of the enrolled subjects, n=76, had an adequate dietary intake of vitamin C (ADI group). Meanwhile, 62%, n=124, had a low dietary intake of vitamin C (LDI group) as compared to the recommended dietary allowances. The fasting plasma level of vitamin C was significantly higher in the ADI group as compared to the LDI group. Oxidative stress in the sera of the LDI group was evidenced by depletion of GSH, low thiols levels, impairment of TAC, an elevation of MDA, and increased NN. In the ADI group, positive correlations were found between plasma vitamin C and serum antioxidant parameters (GSH, thiols, and TAC). Meanwhile, the plasma vitamin C was negatively correlated with serum MDA and NN levels. This study reveals a significant increase of oxidative stress status and reduced antioxidant capacity in sera from healthy young adults with low intake of the dietary antioxidant, vitamin C.
목차
ABSTRACT
INTRODUCTION
SUBJECTS AND METHODS
RESULTS
DISCUSSION
CONCLUSION
REFERENCES
참고문헌 (26)
참고문헌 신청
[학술지(정기간행물)] - Soldati L / 2015 / State of art and science advances on nutrition and nutrigenetics in nutrition-related non-communicable diseases in Middle East / J Transl Med 13 : 40 ~
[학술지(정기간행물)] - Montero J / 2010 / Cholesterol and peroxidized cardiolipin in mitochondrial membrane properties, permeabilization and cell death / Biochim Biophys Acta 1797 : 1217 ~ 1224
[학술지(정기간행물)] - Cooke MS / 1998 / Novel repair action of vitamin C upon in vivo oxidative DNA damage / FEBS Lett 439 : 363 ~ 367
[학술지(정기간행물)] - Kiondo P / 2014 / The effects of vitamin C supplementation on pre-eclampsia in Mulago Hospital, Kampala, Uganda : a randomized placebo controlled clinical trial / BMC Pregnancy Childbirth 14 : 283 ~ 288
[학술지(정기간행물)] - Wu CM / 2014 / -Tocopherol protects keratinocytes against ultraviolet A irradiation by suppressing glutathione depletion, lipid peroxidation and reactive oxygen species generation / Biomed Rep 2 : 419 ~ 423
[학술지(정기간행물)] - Montero J / 2010 / Cholesterol and peroxidized cardiolipin in mitochondrial membrane properties, permeabilization and cell death / Biochim Biophys Acta 1797 : 1217 ~ 1224
[학술지(정기간행물)] - Cooke MS / 1998 / Novel repair action of vitamin C upon in vivo oxidative DNA damage / FEBS Lett 439 : 363 ~ 367
[학술지(정기간행물)] - Kiondo P / 2014 / The effects of vitamin C supplementation on pre-eclampsia in Mulago Hospital, Kampala, Uganda : a randomized placebo controlled clinical trial / BMC Pregnancy Childbirth 14 : 283 ~ 288
[학술지(정기간행물)] - Wu CM / 2014 / -Tocopherol protects keratinocytes against ultraviolet A irradiation by suppressing glutathione depletion, lipid peroxidation and reactive oxygen species generation / Biomed Rep 2 : 419 ~ 423
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UCI(KEPA) : I410-ECN-0101-2016-594-001972847