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논문 기본 정보

자료유형
학술저널
저자정보
Hye-Kyung Jung (Department of Internal Medicine Ewha Womans University School of Medicine Seoul Korea) Seung Joo Kang (Department of Internal Medicine Seoul National University Hospital Healthcare System Gangnam Center) 이용찬 (연세대학교) Hyo-Joon Yang (Department of Internal Medicine Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine) Seon-Young Park (Department of Internal Medicine Chonnam National University Medical School Gwangju Korea) Cheol Min Shin (Department of Internal Medicine Seoul National University Bundang Hospital) Sung Eun Kim (Department of Gastroenterology Kosin University College of Medicine Busan Korea) 임현철 (세브란스병원) Jie-Hyun Kim (Department of Internal Medicine Yonsei University College of Medicine Seoul Korea) Su Youn Nam (Department of Internal Medicine Kyungpook National University Hospital) Woon Geon Shin (Department of Internal Medicine Hallym University College of Medicine) 박재명 (가톨릭대학교) Il Ju Choi (National Cancer Center Goyang Korea) 김재규 (중앙대학교) Miyoung Choi (National Evidence-Based Healthcare Collaborating Agency)
저널정보
대한상부위장관 헬리코박터학회 Korean Journal of Helicobacter Upper Gastrointestinal Research Korean Journal of Helicobacter Upper Gastrointestinal Research Vol.20 No.4
발행연도
2020.1
수록면
261 - 287 (27page)

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초록· 키워드

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Helicobacter pylori (H. pylori) infection is one of the most common infectious diseases worldwide. Although its incidence is gradually decreasing, about half of the world's population still get infected. H. pylori infection is responsible for substantial gastrointestinal morbidity worldwide. It is the most common cause of gastric and duodenal ulcers as well as gastric cancer. Since the revision of the H. pylori Clinical Practice Guidelines in 2013, the eradication rate of H. pylori has gradually decreased with the use of classical triple therapy, wherein amoxicillin, clarithromycin, and proton pump inhibitors are administered, for 7 days. According to a nationwide randomized controlled study conducted by the Korean College of Helicobacter and Upper Gastrointestinal Research released in 2018, the intention-to-treat eradication rate was only 63.9%, which was due to increased antimicrobial resistance induced by the use of antibiotics, especially clarithromycin. The update of clinical practice guideline for treatment of H. pylori was developed based on evidence-based medicine by conducting a meta-analysis. The draft recommendations were finalized after expert consensus on three recommendations regarding the indication for treatment and eight recommendations on the treatment itself. These guidelines are designed to provide patients, nurses, medical school students, policymakers, and clinicians with clinical evidence to guide primary care and treatment of H. pylori infection. These may differ from current medical insurance standards and will be revised further, if necessary, based on research-based evidence.
#Evidence-based medicine #Guideline #Helicobacter pylori #Meta-analysis #Treatment

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참고문헌 (202)

참고문헌 신청
Hunt RH / 2011 / Helicobacter pylori in developing countries. World Gastroenterology Organisation Global Guideline / Gastrointestin Liver Dis 20:299~304 google schola Lee JH / 2019 / Nationwide antibiotic resistance mapping of Helicobacter pylori in Korea : a prospective multicenter study / Helicobacter 24:e12592 google schola Statistics Korea / Vital Statistics of Korea PeriodAnnual 1970~2018 google schola Sugano K / 2015 / Kyoto global consensus report on Helicobacter pylori gastritis / Gut 64:1353~1367 google schola Yeh JM / 2008 / Development of an empirically calibrated model of gastric cancer in two high-risk countries / Cancer Epidemiol Biomarkers Prev 17:1179~1187 google schola

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