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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.6
- 수록면
- 597 - 607 (11page)
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초록· 키워드
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Personalized medicine is tailored medical treatment that targets the individual characteristicsof each patient. Theragnosis, combining diagnosis and therapy, plays an importantrole in selecting appropriate patients. Noninvasive in vivo imaging can trace smallmolecules, antibodies, peptides, nanoparticles, and cells in the body. Recently, imagingmethods have been able to reveal molecular events in cells and tissues. Molecular imagingis useful not only for clinical studies but also for developing new drugs and new treatmentmodalities. Preclinical and early clinical molecular imaging shows biodistribution, pharmacokinetics,mechanisms of action, and efficacy. When therapeutic materials are labeledusing radioisotopes, nuclear imaging with positron emission tomography or gammacamera can be used to treat diseases and monitor therapy simultaneously. Such nuclearmedicine technology is defined as radiation theragnosis. We review the current developmentof drugs and technology for radiation theragnosis using peptides, albumin, nanoparticles,and cells.
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참고문헌 (82)
참고문헌 신청
E.P. Krenning / 1989 / Localisation of endocrine-related tumours with radioiodinated analogue of somatostatin / Lancet 1:242~244
V. Rufini / 2006 / Imaging of neuroendocrine tumors / Semin. Nucl. Med 36:228~247
C. Decristoforo / 1999 / Preparation, 99mTc-labeling, and in vitro characterization of HYNIC and N3S modified RC-160and [Tyr3]octreotide / Bioconjug. Chem 10:431~438
S. Angeletti / 1998 / Use of the somatostatin analogue octreotide to localise and manage somatostatin-producing tumours / Gut 42:792~794
N. Leners / 1996 / Indium-111-pentetreotide uptake in endocrine tumors and lymphoma / J. Nucl. Med 37:916~922
V. Rufini / 2006 / Imaging of neuroendocrine tumors / Semin. Nucl. Med 36:228~247
C. Decristoforo / 1999 / Preparation, 99mTc-labeling, and in vitro characterization of HYNIC and N3S modified RC-160and [Tyr3]octreotide / Bioconjug. Chem 10:431~438
S. Angeletti / 1998 / Use of the somatostatin analogue octreotide to localise and manage somatostatin-producing tumours / Gut 42:792~794
N. Leners / 1996 / Indium-111-pentetreotide uptake in endocrine tumors and lymphoma / J. Nucl. Med 37:916~922
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