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자료유형
학술저널
저자정보
Kang Dayun (Department of Pediatrics Seoul National University Children’s Hospital Seoul the Republic of Korea.) Song Seung Ha (Department of Pediatrics Seoul National University Children’s Hospital Seoul the Republic of Korea.) Ahn Bin (Department of Pediatrics Seoul National University Children’s Hospital Seoul the Republic of Korea.) Lee Bongjin (Department of Pediatrics Seoul National University Children’s Hospital Seoul the Republic of Korea.Department of Pediatrics Seoul National University College of Medicine Seoul the Republic of Korea.) Yun Ki Wook (Department of Pediatrics Seoul National University Children’s Hospital Seoul the Republic of Korea.Department of Pediatrics Seoul National University College of Medicine Seoul the Republic of Korea.)
저널정보
대한소아감염학회 Pediatric Infection and Vaccine Pediatric Infection and Vaccine 제29권 제3호
발행연도
2022.12
수록면
147 - 154 (8page)
DOI
10.14776/piv.2022.29.e19

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The clinical severity of coronavirus disease 2019 (COVID-19) in children is usually mild. Most of the affected patients completely recovered from COVID-19 before being released from approximately 7-day quarantine. However, children with comorbidities are at risk of more severe disease and adverse outcomes. We report three cases of COVID-19-affected adolescents with underlying chronic respiratory difficulty due to neurologic diseases who showed sudden clinical aggravations at the time of discharge, even after full clinical improvement. Patient 1 is a 17-year-old boy with Ullrich congenital muscular dystrophy who had cardiopulmonary arrest 9 days after the initial COVID-19 symptoms. Patient 2 is a 17-year-old girl with intracerebral hemorrhage with infarction in bed-ridden status who had cardiopulmonary arrest 11 days after the initial symptoms. Patient 3 is a 12-year-old boy with intraventricular hemorrhage with hydrocephalus in bed-ridden status who showed multiorgan failure 10 days after the initial symptoms. Remdesivir, dexamethasone, and empirical antibiotics were administered with mechanical ventilation and intensive unit care. Among the three patients, two (patients 1 and 3) were alive, and one (patient 2) expired. Clinicians caring for adolescents with chronic neurologic and/or pulmonary disease should keep in mind that these patients could have sudden deterioration after recovery from the acute phase of COVID-19 around or after the time of discharge.

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